Moe is the last butcher left in Little Italy. He used to be in Little Italy, anyway, before all the Italians left and the upscale boutiques moved in. The neighborhood is now known as Nolita, as it is north of (what remains of) Little Italy.
Also, as you may have noticed, this meat market looks an awful lot like an art gallery. That's because it is an art gallery; Moe's shop is actually located across the street. The artist whose work is for sale here is no Johnny-come-lately, however; he's an elderly Hawaiian man who's owned this building since 1977.